Toma Coman, Viorica Chiurciu


The purpose of the paper was to investigate the virucide activity of a disinfecting, product based on quaternary amines mixed with glutaraldehyde. The virucide activity was determined against the viruses of the Newcastle disease (ND), aviary influenza (AI), infectious aviary bursitis (IAB) and the infectious aviary bronchitis (IB). Solutions in phosphate buffered saline (PBS), each of 10-4 DIE50/ml of the mentioned viruses were put into contact for 10, 30 and 60 minutes with Decontaminol 0.1% dilutions in sterile hard water4. After the time for contact ended, the mixtures of virus and Decontaminol have been into SPF embryos, with an age of 9 days. Each embryo received 2x10-3 DIE50. The alanto-amniotic fluid was examined for hemaglutinant activities (ND, AI), the embryos for the presence of the specific lesions of IAB, IB. Decontaminol 0.1% dilution had an intense virucide activity (100%) against ND, AI and IAB viruses, which were destroyed after 10 minutes of contact. IAB virus was by the 0.1% Decontaminol solution after 60 minutes of contact.

Key words: quaternary amines, glutaraldehyde, virucide activity, aviary viruses (ND, AI, IAB, IB)

4 The hard water contains 300 µl/calcium carbonate.

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